Dihydrobenzofurans

Dihydrobenzofuran frameworks sit between benzofuran planarity and cyclic-ether flexibility, giving chemists a partially reduced fused oxygen scaffold with more shape. They are useful when a series needs an oxygen-containing bicyclic motif that is less flat than a fully aromatic analogue but still recognisable. This category is relevant to medicinal chemistry, chiral scaffold work, and oxygen-heterocycle exploration.